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http://bura.brunel.ac.uk/handle/2438/5852Full metadata record
| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Nayak, A | - |
| dc.contributor.author | Ansar, R | - |
| dc.contributor.author | Verma, SK | - |
| dc.contributor.author | Bonifati, DM | - |
| dc.contributor.author | Kishore, U | - |
| dc.date.accessioned | 2011-09-23T13:33:52Z | - |
| dc.date.available | 2011-09-23T13:33:52Z | - |
| dc.date.issued | 2011 | - |
| dc.identifier.citation | Neurology Research International, 2011: 563784, 2011 | en_US |
| dc.identifier.issn | 2090-1860 | - |
| dc.identifier.uri | http://bura.brunel.ac.uk/handle/2438/5852 | - |
| dc.description | Copyright © 2011 Annapurna Nayaketal. This article has been made available through the Brunel Open Access Publishing Fund. | en_US |
| dc.description.abstract | Huntington's disease (HD) is a progressive neurodegenerative disorder that is caused by abnormal expansion of CAG trinucleotide repeats. Neuroinflammation is a typical feature of most neurodegenerative diseases that leads to an array of pathological changes within the affected areas in the brain. The neurodegeneration in HD is also caused by aberrant immune response in the presence of aggregated mutant huntingtin protein. The effects of immune activation in HD nervous system are a relatively unexplored area of research. This paper summarises immunological features associated with development and progression of HD. | en_US |
| dc.description.sponsorship | U. Kishore acknowledges funding via BRIEF and Brunel University’s strategic funding for the Centre of Infection, Immunity and Disease Mechanisms. | en_US |
| dc.language | eng | - |
| dc.language.iso | en | en_US |
| dc.publisher | Pubmed Central | en_US |
| dc.title | Huntington's disease: An immune perspective | en_US |
| dc.type | Research Paper | en_US |
| dc.identifier.doi | http://dx.doi.org/10.1155/2011/563784 | - |
| pubs.organisational-data | /Brunel | - |
| pubs.organisational-data | /Brunel/Brunel (Active) | - |
| pubs.organisational-data | /Brunel/Brunel (Active)/School of Health Science & Social Care | - |
| pubs.organisational-data | /Brunel/Research Centres (RG) | - |
| pubs.organisational-data | /Brunel/Research Centres (RG)/CIIDM | - |
| pubs.organisational-data | /Brunel/School of Health Sciences and Social Care (RG) | - |
| pubs.organisational-data | /Brunel/School of Health Sciences and Social Care (RG)/CIIDM | - |
| Appears in Collections: | Biological Sciences Publications Brunel OA Publishing Fund Dept of Life Sciences Research Papers | |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Fulltext.pdf | 1.48 MB | Adobe PDF | View/Open |
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