Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/28059
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dc.contributor.authorAbafe, OA-
dc.contributor.authorChokwe, T-
dc.date.accessioned2024-01-19T17:55:55Z-
dc.date.available2021-12-13-
dc.date.available2024-01-19T17:55:55Z-
dc.date.issued2021-12-13-
dc.identifierORCID iD: Ovokeroye Akpojevwe Abafe https://orcid.org/0000-0002-5672-6463-
dc.identifier3-
dc.identifier.citationAbafe, O.A. and Chokwe, T. (2021) 'Determination and dietary risk assessment of neonicotinoid and insect growth regulators in honey', Journal of Environmental Exposure Assessment, 1 (1), 3, pp. 1 - 15. doi: 10.20517/jeea.2021.04.en_US
dc.identifier.urihttps://bura.brunel.ac.uk/handle/2438/28059-
dc.descriptionAvailability of data and materials: Additional data for this study are presented in the supplementary information, available online at: https://f.oaes.cc/files/jeea/jeea-2021-4-SupplementaryMaterials.pdf .en_US
dc.description.abstractCopyright © The Author(s) 2021. Aim: The aim of this study was to determine the presence, concentrations, dietary intake, and risk of residues of neonicotinoids (NEO) and insect growth regulators (IGR) in commercially available honey in South Africa. Methods: Sample preparation for honey was based on the “dilute and shoot” principle, followed by analysis using an internally validated ultra-high-performance liquid chromatographic coupled to tandem mass spectrometric method. Estimated daily intake and acute and chronic hazard quotients were determined to measure human exposure and health risk to NEO and IGR as well as the risk posed to honeybee. Results: NEO and IGR were detected in 50% and 21% of the 115 honey samples, respectively. The average concentration ranged 0.062-6.50 µgkg-1 and 0.479-1.644 µgkg-1 for NEO and IGR, respectively. While acetamiprid was the most detected (24.35%) NEO, imidacloprid presented the highest concentration (16.945 µg kg-1) in a sample. IGR co-occurred at variable concentrations with NEO in honey samples. The estimated daily intakes (EDI) of NEO and IGR ranged from 9.35 × 10-7 to 4.93 × 10-6 mg kg-1 bwd-1. The chronic hazard quotient (HQc) and acute hazard quotient (HQa) for NEO and IGR were considerably < 1, indicating negligible risk to human health and honeybee population. Conclusion: A UHPLC-MS/MS method was validated for the simultaneous determination of neonicotinoids and insect growth regulators in honey. Overall, the result of the present study confirms the widespread occurrence of NEO and IGR in honey consumed in South Africa. The EDIs, HQc, and HQa indicate that exposure to all target NEO and IGR via honey consumption constitutes negligible human health risk; however, the consequences of multiple routes of exposure to NEO and IGR cannot be overemphasized.en_US
dc.description.sponsorshipAgricultural Research Council of South Africa for financial supporten_US
dc.format.extent1 - 15-
dc.format.mediumElectronic-
dc.languageEnglish-
dc.language.isoen_USen_US
dc.publisherOAE Publishingen_US
dc.relation.urihttps://f.oaes.cc/files/jeea/jeea-2021-4-SupplementaryMaterials.pdf-
dc.rightsCopyright © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, sharing, adaptation, distribution and reproduction in any medium or format, for any purpose, even commercially, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.-
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/-
dc.subjectneonicotinoidsen_US
dc.subjectinsect growth regulatoren_US
dc.subjecthoneyen_US
dc.subjectdietary risken_US
dc.titleDetermination and dietary risk assessment of neonicotinoid and insect growth regulators in honeyen_US
dc.typeArticleen_US
dc.identifier.doihttps://doi.org/10.20517/jeea.2021.04-
dc.relation.isPartOfJournal of Environmental Exposure Assessment-
pubs.issue1-
pubs.publication-statusPublished-
pubs.volume1-
dc.identifier.eissn2771-5949-
dc.rights.holderThe Author(s)-
Appears in Collections:Dept of Life Sciences Research Papers

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