Brunel University Research Archive(BURA) preserves and enables easy and open access to all
types of digital content. It showcases Brunel's research outputs.
Research contained within BURA is open access, although some publications may be subject
to publisher imposed embargoes. All awarded PhD theses are also archived on BURA.
Please use this identifier to cite or link to this item:
http://bura.brunel.ac.uk/handle/2438/26164| Title: | 3D genome organization |
| Authors: | Silahtaroglu, A Bridger, JM Lei, EP |
| Keywords: | genetics;molecular medicine |
| Issue Date: | 22-Dec-2022 |
| Publisher: | Springer Nature |
| Citation: | Silahtaroglu, A., Bridger, J.M. and Lei, E.P. (2022) '3D genome organization', Scientific Reports, 2022, 12, 22106, pp. 1 - 2. doi: 10.1038/s41598-022-26725-7. |
| Abstract: | Copyright © The Author(s) 2022. Our genomes are highly organized spatially in three-dimensions (3D). In interphase nuclei, the genome is anchored and regulated by various nuclear scaffolds and structures, including the nuclear lamina at the nuclear edge, and nucleoli located more internally within the nucleoplasm. Recently, great effort has been made to understand the intricacies of 3D genome organization and its relevance to genomic and nuclear function. Over the years, many concepts, mathematical models, visual and biochemical methods, and analysis pipelines have been presented to study various aspects of this organization in a multidisciplinary manner, such as is also reflected within this collection. |
| URI: | https://bura.brunel.ac.uk/handle/2438/26164 |
| DOI: | https://doi.org/10.1038/s41598-022-26725-7 |
| Other Identifiers: | ORCID iDs: Asli Silahtaroglu https://orcid.org/0000-0001-6181-2705; Joanna Bridger https://orcid.org/0000-0003-3999-042X. |
| Appears in Collections: | Dept of Life Sciences Research Papers |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| FullText.pdf | Copyright © The Author(s) 2022. Rights and permissions: Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/. | 841.17 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License
