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Please use this identifier to cite or link to this item: http://bura.brunel.ac.uk/handle/2438/9361
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dc.contributor.authorRasponi, M-
dc.contributor.authorGazaneo, A-
dc.contributor.authorBonomi, A-
dc.contributor.authorOcchetta, P-
dc.contributor.authorCavicchini, L-
dc.contributor.authorCocce, V-
dc.contributor.authorFiore, GB-
dc.contributor.authorPessina, A-
dc.contributor.authorRedaelli, A-
dc.contributor.author4th Micro and Nano Flows Conference (MNF2014)-
dc.date.accessioned2014-12-04T16:05:59Z-
dc.date.available2014-12-04T16:05:59Z-
dc.date.issued2014-
dc.identifier.citation4th Micro and Nano Flows Conference, University College London, UK, 7-10 September 2014, Editors CS König, TG Karayiannis and S. Balabanien_US
dc.identifier.isbn978-1-908549-16-7-
dc.identifier.urihttp://bura.brunel.ac.uk/handle/2438/9361-
dc.descriptionThis paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community, www.nanopaprika.eu.en_US
dc.description.abstractIn the last twenty years, one of the main goals in the drug discovery field has been the development of reliable in vitro models. In particular, in 2006 the European Centre for the Validation of Alternative Methods (ECVAM) has approved the Colony forming Unit-Granulocytes-Macrophages (CFU-GM) test, which is the first and currently unique test applied to evaluate the myelotoxicity of xenobiotics in vitro. The present work aimed at miniaturizing this in vitro assay by developing and validating a Lab-on-Chip (LoC) platform consisting of a high number of bioreactor chambers with screening capabilities in a high-throughput regime.en_US
dc.language.isoenen_US
dc.publisherBrunel University Londonen_US
dc.relation.ispartofseriesID 114-
dc.subjectLab-on-Chipen_US
dc.subjectMicrofluidicsen_US
dc.subjectClonogenic testen_US
dc.subjectCFU-GMen_US
dc.subjectCBMNCen_US
dc.titleLab-on-Chip for Testing Myelotoxic Effect of Drugs and Chemicalsen_US
dc.typeConference Paperen_US
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