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DC Field | Value | Language |
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dc.contributor.author | Zhang, B | - |
dc.contributor.author | Morgan, M | - |
dc.contributor.author | Teoh, XY | - |
dc.contributor.author | Mackay, R | - |
dc.contributor.author | Ermler, S | - |
dc.contributor.author | Narayan, R | - |
dc.date.accessioned | 2024-04-10T14:37:36Z | - |
dc.date.available | 2024-04-10T14:37:36Z | - |
dc.date.issued | 2024-04-14 | - |
dc.identifier | ORCiD ID Bin Zhang https://orcid.org/0000-0003-2374-0127 | - |
dc.identifier | ORCiD ID Roger Narayan https://orcid.org/0000-0002-2673-0939 | - |
dc.identifier | ORCiD ID Ruth Mackay https://orcid.org/0000-0002-6456-6914 | - |
dc.identifier | ORCiD ID Sibylle Ermler https://orcid.org/0000-0002-2626-9548 | - |
dc.identifier | ORCiD ID Meagan Morgan https://orcid.org/0000-0002-6637-9493 | - |
dc.identifier | ORCiD ID Xin-Yi Teoh https://orcid.org/0000-0002-7548-0315 | - |
dc.identifier.citation | Zhang, B. et al. (2024). ‘Recent advances in 3D printing for in vitro cancer models’ in Journal of Applied Physics. Vol.135 (14)., pp.1 - 19. DOI:https://doi.org/10.1063/5.0200726. | en_US |
dc.identifier.issn | 0021-8979 | - |
dc.identifier.uri | http://bura.brunel.ac.uk/handle/2438/28741 | - |
dc.description | This paper is part of the special topic, Physics of 3D Printing. | en_US |
dc.description.abstract | 3D printing techniques allow for the precise placement of living cells, biological substances, and biochemical components, establishing themselves as a promising approach in bioengineering. Recently, 3D printing has been applied to develop human-relevant in vitro cancer models with highly controlled complexity and as a potential method for drug screening and disease modeling. Compared to 2D culture, 3D-printed in vitro cancer models more closely replicate the in vivo microenvironment. Additionally, they offer a reduction in the complexity and ethical issues associated with using in vivo animal models. This focused review discusses the relevance of 3D printing technologies and the applied cells and materials used in cutting-edge in vitro cancer models and microfluidic device systems. Future prospective solutions were discussed to establish 3D-printed in vitro models as reliable tools for drug screening and understanding cancer disease mechanisms. | en_US |
dc.description.sponsorship | Brunel Research Interdisciplinary Labs (BRIL) and Brief Award (BRIEF) | en_US |
dc.publisher | American Institute of Physics | en_US |
dc.rights | © 2024 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution-NonCommercial NoDerivs 4.0 International (CC BY-NC-ND) license (https://creativecommons.org/licenses/by-nc-nd/4.0/). https://doi.org/10.1063/5.0200726 | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0/ | - |
dc.subject | 3D printing | en_US |
dc.subject | Microfluidic devices | en_US |
dc.subject | Bioengineering | en_US |
dc.subject | Pharmaceuticals | en_US |
dc.subject | Organs | en_US |
dc.subject | Animal model | en_US |
dc.subject | Cancer treatment | en_US |
dc.subject | Cell lines | en_US |
dc.subject | 3D bioprinting | en_US |
dc.title | Recent Advances in 3D printing for in vitro cancer models | en_US |
dc.type | Article | en_US |
dc.identifier.doi | http://dx.doi.org/10.1063/5.0200726 | - |
dc.relation.isPartOf | Journal of Applied Physics | - |
pubs.publication-status | Published | - |
Appears in Collections: | Dept of Mechanical and Aerospace Engineering Research Papers |
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FullText.pdf | © 2024 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution-NonCommercial NoDerivs 4.0 International (CC BY-NC-ND) license (https://creativecommons.org/licenses/by-nc-nd/4.0/). | 3.71 MB | Adobe PDF | View/Open |
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