Please use this identifier to cite or link to this item:
http://bura.brunel.ac.uk/handle/2438/26634
Title: | Prevalence and incidence of chronic conditions among adults with cerebral palsy: A systematic review and meta-analysis |
Authors: | Ryan, JM Albairami, F Hamilton, T Cope, N Amirmudin, NA Manikandan, M Kilbride, C Stevenson, VL Livingstone, E Fortune, J |
Issue Date: | 20-Feb-2023 |
Publisher: | Wiley on behalf of Mac Keith Press |
Citation: | Ryan, J.M. et al. (2023) 'Prevalence and incidence of chronic conditions among adults with cerebral palsy: A systematic review and meta-analysis', Developmental Medicine and Child Neurology, 65 (9), pp. 1174 - 1189. doi: 10.1111/dmcn.15526. |
Abstract: | Aim: To assess the prevalence and incidence of chronic conditions among adults with cerebral palsy (CP) and compare them to the prevalence and incidence among adults without CP. Method: We searched MEDLINE and Embase for studies reporting the prevalence or incidence of one or more chronic conditions among adults with CP. Two independent reviewers screened titles, abstracts, and full-text articles. Two independent reviewers extracted data relating to prevalence and incidence and appraised study quality. We performed random-effects meta-analyses to pool prevalence and incidence. Results: We identified 69 studies; 65 reported the prevalence of 53 conditions and 13 reported the incidence of 21 conditions. At least 20% of adults had the following conditions: depression (21%); anxiety (21%); mood affective disorders (23%); asthma (24%); hypertension (26%); epilepsy (28%); urinary incontinence (32%); malnutrition (38%); and scoliosis (46%). Adults with CP were more likely to have type 2 diabetes, anxiety, bipolar disorder, depression, schizophrenia, hypertension, ischaemic heart disease, stroke, cerebrovascular disease, asthma, liver disease, osteoarthritis, osteoporosis, underweight, and chronic kidney disease than adults without CP. Interpretation: These data from 18 countries, which provide an international perspective, may be used to promote awareness, identify targets for intervention, and inform the development of appropriate supports for adults with CP. |
Description: | Data availability statement: Data sharing is not applicable to this article as no new data were created or analyzed in this study. Supporting information is available online at https://onlinelibrary.wiley.com/doi/10.1111/dmcn.15526#support-information-section . |
URI: | https://bura.brunel.ac.uk/handle/2438/26634 |
DOI: | https://doi.org/10.1111/dmcn.15526 |
ISSN: | 0012-1622 |
Other Identifiers: | ORCiD: Jennifer M. Ryan https://orcid.org/0000-0003-3768-2132 ORCiD: Manjula Manikandan https://orcid.org/0000-0003-2631-8482 ORCiD: Cherry Kilbride https://orcid.org/0000-0002-2045-1883 ORCiD: Jennifer Fortune https://orcid.org/0000-0001-8971-1236 |
Appears in Collections: | Dept of Health Sciences Research Papers |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
FullText.pdf | Copyright © 2023 The Authors. Developmental Medicine & Child Neurology published by John Wiley & Sons Ltd on behalf of Mac Keith Press. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. | 248.74 kB | Adobe PDF | View/Open |
This item is licensed under a Creative Commons License