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DC Field | Value | Language |
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dc.contributor.author | Kilbride, C | - |
dc.contributor.author | Scott, DJM | - |
dc.contributor.author | Butcher, T | - |
dc.contributor.author | Norris, M | - |
dc.contributor.author | Warland, A | - |
dc.contributor.author | Anokye, N | - |
dc.contributor.author | Cassidy, E | - |
dc.contributor.author | Baker, K | - |
dc.contributor.author | Athanasiou, DA | - |
dc.contributor.author | Singla-Buxarrais, G | - |
dc.contributor.author | Nowicky, A | - |
dc.contributor.author | Ryan, J | - |
dc.date.accessioned | 2022-01-30T19:15:27Z | - |
dc.date.available | 2022-01-30T19:15:27Z | - |
dc.date.issued | 2022-02-28 | - |
dc.identifier | ORCiD: Cherry Kilbride http://orcid.org/0000-0002-2045-1883 | - |
dc.identifier | ORCiD: Meriel Norris https://orcid.org/0000-0001-7779-5612 | - |
dc.identifier | ORCiD: Alyson Warland https://orcid.org/0000-0002-4629-0395 | - |
dc.identifier | ORCiD: Nana Anokye https://orcid.org/0000-0003-3615-344X | - |
dc.identifier | ORCiD: Karen Baker https://orcid.org/0000-0002-5354-3901 | - |
dc.identifier | ORCiD: Alexander Nowicky https://orcid.org/0000-0001-8955-4349 | - |
dc.identifier | ORCiD: Jennifer Ryan https://orcid.org/0000-0003-3768-2132 | - |
dc.identifier | e052555 | - |
dc.identifier.citation | Kilbride, C. et al. (2022) 'Safety, feasibility, acceptability and preliminary effects of the Neurofenix platform for Rehabilitation via HOMe Based gaming exercise for the Upper-limb post Stroke (RHOMBUS): results of a feasibility intervention study', BMJ Open, 12 (2), e052555, pp. 1 - 11. doi: 10.1136/bmjopen-2021-052555. | en_US |
dc.identifier.uri | https://bura.brunel.ac.uk/handle/2438/24037 | - |
dc.description | Data availability statement: No data are available. Participants did not consent for datasets to be stored or accessed outside of the research team. Therefore, no datasets have been made publicly available. Acknowledgments: The authors would like to thank two stroke survivors who assisted the development of the intervention and advised on the protocol, trial documentation and dissemination. Further thanks to the group facilitators of Different Strokes and the Action for Rehabilitation from Neurological Injury. Thanks to Professor Christina Victor for her support. | en_US |
dc.description.abstract | Objectives To investigate the safety, feasibility and acceptability of the Neurofenix platform for home-based rehabilitation of the upper limb (UL). Design A non-randomised intervention design with a parallel process evaluation. Setting Participants’ homes, South-East England. Participants Thirty adults (≥18 years), minimum 12-week poststroke, not receiving UL rehabilitation, scoring 9–25 on the Motricity Index (elbow and shoulder), with sufficient cognitive and communicative abilities to participate. Interventions Participants were trained to use the platform, followed by 1 week of graded game-play exposure and 6-week training, aiming for a minimum 45 min, 5 days/week. Outcomes Safety was determined by assessing pain and poststroke fatigue at 8 and 12 weeks, and adverse events (AEs). Impairment, activity and participation outcomes were measured. Intervention feasibility was determined by the amount of specialist training and support required to complete the intervention, time and days spent training, and number of UL movements performed. Acceptability was assessed by a satisfaction questionnaire and semistructured interviews. Results Participants (14 women; mean (SD) age 60.0 (11.3) years) were a median of 4.9 years poststroke (minimum-maximum: 1–28 years). Twenty-seven participants completed the intervention. The odds of having shoulder pain were lower at 8 weeks (OR 0.45, 95% CI 0.24 to 0.83, p=0.010) and 12 weeks (OR 0.46, 95% CI 0.25 to 0.86, p=0.014) compared with baseline. Fugl-Meyer upper extremity, Motor Activity Log and passive range of movement improved. No other gains were recorded. Poststroke fatigue did not change. Thirty mild and short-term AEs and one serious (unrelated) AE were reported by 19 participants. Participants trained with the platform for a median of 17.4 hours over 7 weeks (minimum-maximum: 0.3–46.9 hours), equating to a median of 149 min per week. The median satisfaction score was 36 out of 40. Conclusion The Neurofenix platform is a safe, feasible and well accepted way to support UL training for people at least three months poststroke. Trial registration number ISRCTN60291412. | - |
dc.description.sponsorship | Innovate UK grant number 104188. | en_US |
dc.format.extent | 1 - 11 | - |
dc.format.medium | Electronic | - |
dc.language.iso | en | en_US |
dc.publisher | BMJ Publishing Group | en_US |
dc.rights | Copyright information: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/. | - |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | - |
dc.subject | rehabilitation | en_US |
dc.subject | stroke | en_US |
dc.subject | upper-limb | en_US |
dc.subject | virtual reality | en_US |
dc.subject | gaming | en_US |
dc.subject | protocol | en_US |
dc.subject | feasibility | en_US |
dc.title | Safety, feasibility, acceptability and preliminary effects of the Neurofenix platform for Rehabilitation via HOMe Based gaming exercise for the Upper-limb post Stroke (RHOMBUS): results of a feasibility intervention study | en_US |
dc.type | Article | en_US |
dc.identifier.doi | https://doi.org/10.1136/bmjopen-2021-052555 | - |
dc.relation.isPartOf | BMJ Open | - |
pubs.issue | 2 | - |
pubs.publication-status | Published | - |
pubs.volume | 12 | - |
dc.identifier.eissn | 2044-6055 | - |
Appears in Collections: | Dept of Health Sciences Research Papers |
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