Progressive resistance training for adolescents with cerebral palsy: the STAR randomized controlled trial

Abstract

© 2020 The Authors. Aim To evaluate the effect of progressive resistance training of the ankle plantar flexors on gait efficiency, activity, and participation in adolescents with cerebral palsy (CP).

Method Sixty‐four adolescents (10–19y; 27 females, 37 males; Gross Motor Function Classification System [GMFCS] levels I–III) were randomized to 30 sessions of resistance training (10 supervised and 20 unsupervised home sessions) over 10 weeks or usual care. The primary outcome was gait efficiency indicated by net non dimensional oxygen cost (NNcost). Secondary outcomes included physical activity, gross motor function, participation, muscle strength, muscle and tendon size, and muscle and tendon stiffness. Analysis was intention‐to‐treat.

Results Median attendance at the 10 supervised sessions was 80% (range 40–100%). There was no between‐group difference in NNcost at 10 (mean difference: 0.02, 95% confidence interval [CI] –0.07 to 0.11, p =0.696) or 22 weeks (mean difference: –0.08, 95% CI –0.18 to 0.03, p =0.158). There was also no evidence of between‐group differences in secondary outcomes at 10 or 22 weeks. There were 123 adverse events reported by 27 participants in the resistance training group.

Interpretation We found that 10 supervised sessions and 20 home sessions of progressive resistance training of the ankle plantar flexors did not improve gait efficiency, muscle strength, activity, participation, or any biomechanical outcome among adolescents with CP.