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Title: | Nanoengineering the antibacterial activity of biosynthesized nanoparticles of TiO<inf>2</inf>, Ag and Au and their nanohybrids with Portobello mushroom spores (PMS) (TiO<inf>x</inf>/PMS, Ag/PMS and Au/PMS) and making them optically self-indicating |
Authors: | Jaffer Al-Timini, IA Sermon, PA Burghal, AA Salih, AA Alrubaya, IMN |
Issue Date: | 2016 |
Citation: | Proceedings of SPIE - The International Society for Optical Engineering, 2016, 9930 (13) |
Abstract: | Results show that nanoparticles (NPs) can be biosynthesized at room temperature on the reductive and chelating surfaces of Portobello mushroom spores (PMS). Using this green approach TiOx, Ag, Au, Ag-TiOx and Au-TiOx NPs have been prepared. These were characterized by TEM, SIMS and FTIR-FTIR. TiOx/PMS, Ag-TiOx/PMS, Au-TiOx/PMS and Ag/PMS were active in bacterial inhibition towards Eschericia coli and Staphylococcus aureus, but Au/PMS was not active (suggesting a strong Au-PMS interaction). TiOx/PMS, Ag/PMS and Ag-TiOx/PMS were equally active in an antibacterial and an antifungal sense when tested against Asperillus and Candide. All samples (except Ag-TiOx/PMS and Au-TiOx/PMS) showed an interesting interaction with DNA. We report on the process of fine-tuning these antibacterial properties, progress on making these nanomaterials optically selfindicating and movement towards optical control of their antibacterial activity. Au-TiOx/PMS shows a surface plasmon resonance (SPR) with a maximum at 518 nm that might be useful in following its anti-bacterial properties (i.e. making the bionanomaterial self-indicating). The future of such green bio-nanomaterials is strong. |
URI: | https://bura.brunel.ac.uk/handle/2438/16034 |
DOI: | https://doi.org/10.1117/12.2237643 |
ISBN: | 9781510602519 |
ISSN: | 0277-786X 1996-756X |
Appears in Collections: | Dept of Mechanical and Aerospace Engineering Research Papers |
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