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|Title:||Whole genome analysis of a schistosomiasis-transmitting freshwater snail|
|Publisher:||Nature Publishing Group|
|Citation:||Nature Communications, 8: pp. 1-11, (2017)|
|Abstract:||Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.|
|Appears in Collections:||Dept of Life Sciences Research Papers|
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