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http://bura.brunel.ac.uk/handle/2438/10629
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DC Field | Value | Language |
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dc.contributor.author | Liverani, S | - |
dc.contributor.author | Anderson, PE | - |
dc.contributor.author | Edwards, KD | - |
dc.contributor.author | Millar, AJ | - |
dc.contributor.author | Smith, JQ | - |
dc.date.accessioned | 2015-04-23T08:36:27Z | - |
dc.date.available | 2009 | - |
dc.date.available | 2015-04-23T08:36:27Z | - |
dc.date.issued | 2009 | - |
dc.identifier.citation | Bayesian Analysis, 2009, 4 (3), pp. 539 - 572 | en_US |
dc.identifier.issn | 1936-0975 | - |
dc.identifier.issn | 1931-6690 | - |
dc.identifier.uri | http://bura.brunel.ac.uk/handle/2438/10629 | - |
dc.description.abstract | Because of the huge number of partitions of even a moderately sized dataset, even when Bayes factors have a closed form, in model-based clustering a comprehensive search for the highest scoring (MAP) partition is usually impossible. However, when each cluster in a partition has a signature and it is known that some signatures are of scientific interest whilst others are not, it is possible, within a Bayesian framework, to develop search algorithms which are guided by these cluster signatures. Such algorithms can be expected to find better partitions more quickly. In this paper we develop a framework within which these ideas can be formalized. We then briefly illustrate the efficacy of the proposed guided search on a microarray time course data set where the clustering objective is to identify clusters of genes with different types of circadian expression profiles. | en_US |
dc.format.extent | 539 - 572 | - |
dc.format.extent | 539 - 572 | - |
dc.language | eng | - |
dc.language.iso | en | en_US |
dc.publisher | International Society for Bayesian Analysis (ISBA) | en_US |
dc.subject | Bayesian | en_US |
dc.subject | Circardian Expression Profiles | en_US |
dc.subject | Genetics | en_US |
dc.subject | Posterior Probability Distribution | en_US |
dc.title | Efficient utility-based clustering over high dimensional partition spaces | en_US |
dc.type | Article | en_US |
dc.identifier.doi | http://dx.doi.org/10.1214/09-BA420 | - |
dc.relation.isPartOf | Bayesian Analysis | - |
dc.relation.isPartOf | Bayesian Analysis | - |
pubs.issue | 3 | - |
pubs.issue | 3 | - |
pubs.volume | 4 | - |
pubs.volume | 4 | - |
pubs.organisational-data | /Brunel | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division/College of Engineering, Design and Physical Sciences | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division/College of Engineering, Design and Physical Sciences/Dept of Mathematics | - |
pubs.organisational-data | /Brunel/Brunel Staff by College/Department/Division/College of Engineering, Design and Physical Sciences/Dept of Mathematics/Mathematical Sciences | - |
Appears in Collections: | Dept of Electronic and Electrical Engineering Research Papers |
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FullText.pdf | 6.11 MB | Adobe PDF | View/Open |
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